6ds0: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor==
-<StructureSection load='6ds0' size='340' side='right' caption='[[6ds0]], [[Resolution|resolution]] 3.19&Aring;' scene=''>
+<StructureSection load='6ds0' size='340' side='right'caption='[[6ds0]], [[Resolution|resolution]] 3.19&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6ds0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DS0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DS0 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6ds0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DS0 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=H8M:(1S)-1-[(2-chloro-3,4-dimethoxyphenyl)methyl]-6-methyl-2,3,4,9-tetrahydro-1H-beta-carboline'>H8M</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.188&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HTR2B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=H8M:(1~{S})-1-[(2-chloranyl-3,4-dimethoxy-phenyl)methyl]-6-methyl-2,3,4,9-tetrahydro-1~{H}-pyrido[3,4-b]indole'>H8M</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ds0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ds0 OCA], [http://pdbe.org/6ds0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ds0 RCSB], [http://www.ebi.ac.uk/pdbsum/6ds0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ds0 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ds0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ds0 OCA], [https://pdbe.org/6ds0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ds0 RCSB], [https://www.ebi.ac.uk/pdbsum/6ds0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ds0 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/5HT2B_HUMAN 5HT2B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
+[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/5HT2B_HUMAN 5HT2B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 19: / Line 19: @@
 </div>
 <div class="pdbe-citations 6ds0" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[5-hydroxytryptamine receptor 3D structures|5-hydroxytryptamine receptor 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Bacillus coli migula 1895]]
+[[Category: Escherichia coli]]
-[[Category: Agegnehu, B]]
+[[Category: Homo sapiens]]
-[[Category: Che, T]]
+[[Category: Large Structures]]
-[[Category: Jin, J]]
+[[Category: Agegnehu B]]
-[[Category: Lansu, K]]
+[[Category: Che T]]
-[[Category: Liu, J]]
+[[Category: Jin J]]
-[[Category: McCorvy, J D]]
+[[Category: Lansu K]]
-[[Category: Olsen, R H.J]]
+[[Category: Liu J]]
-[[Category: Roth, B L]]
+[[Category: McCorvy JD]]
-[[Category: Tribo, A R]]
+[[Category: Olsen RHJ]]
-[[Category: Wacker, D]]
+[[Category: Roth BL]]
-[[Category: Wang, S]]
+[[Category: Tribo AR]]
-[[Category: Gpcr]]
+[[Category: Wacker D]]
-[[Category: Lisuride]]
+[[Category: Wang S]]
-[[Category: Membrane protein]]
-[[Category: Setotonin receptor]]