6ebv: Difference between revisions

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New page: '''Unreleased structure''' The entry 6ebv is ON HOLD Authors: Chen, Y., Antoshchenko, T., Strauss, E., Barnard, L., Huang, Y.H., Park, H. Description: Staphylococcus aureus Type II pan...
 
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'''Unreleased structure'''


The entry 6ebv is ON HOLD
==Staphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Deoxy-N7-Pan==
<StructureSection load='6ebv' size='340' side='right'caption='[[6ebv]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6ebv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EBV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=27Q:N-HEPTYL-N~3~-[(2R)-2-HYDROXY-3,3-DIMETHYL-4-(PHOSPHONOOXY)BUTANOYL]-BETA-ALANINAMIDE'>27Q</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ebv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ebv OCA], [https://pdbe.org/6ebv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ebv RCSB], [https://www.ebi.ac.uk/pdbsum/6ebv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ebv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COAW_STAA8 COAW_STAA8] Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.<ref>PMID:12760898</ref>


Authors: Chen, Y., Antoshchenko, T., Strauss, E., Barnard, L., Huang, Y.H., Park, H.
==See Also==
 
*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]]
Description: Staphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Deoxy-N7-Pan
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Antoshchenko, T]]
__TOC__
[[Category: Barnard, L]]
</StructureSection>
[[Category: Huang, Y.H]]
[[Category: Large Structures]]
[[Category: Strauss, E]]
[[Category: Staphylococcus aureus]]
[[Category: Chen, Y]]
[[Category: Antoshchenko T]]
[[Category: Park, H]]
[[Category: Barnard L]]
[[Category: Chen Y]]
[[Category: Huang YH]]
[[Category: Park H]]
[[Category: Strauss E]]

Latest revision as of 17:40, 13 March 2024

Staphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Deoxy-N7-PanStaphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Deoxy-N7-Pan

Structural highlights

6ebv is a 4 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

COAW_STAA8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.[1]

See Also

References

  1. ↑ Choudhry AE, Mandichak TL, Broskey JP, Egolf RW, Kinsland C, Begley TP, Seefeld MA, Ku TW, Brown JR, Zalacain M, Ratnam K. Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections. Antimicrob Agents Chemother. 2003 Jun;47(6):2051-5. PMID:12760898 doi:10.1128/AAC.47.6.2051-2055.2003

6ebv, resolution 3.00Å

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