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==Cryo-EM of the GTP-bound human dynamin-1 polymer assembled on the membrane in the super constricted state==
==Cryo-EM of the GTP-bound human dynamin-1 polymer assembled on the membrane in the super constricted state==
<StructureSection load='6dlv' size='340' side='right' caption='[[6dlv]], [[Resolution|resolution]] 10.10&Aring;' scene=''>
<SX load='6dlv' size='340' side='right' viewer='molstar' caption='[[6dlv]], [[Resolution|resolution]] 10.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6dlv]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DLV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DLV FirstGlance]. <br>
<table><tr><td colspan='2'>[[6dlv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DLV FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6dlu|6dlu]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.1&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dynamin_GTPase Dynamin GTPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.5 3.6.5.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dlv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dlv OCA], [https://pdbe.org/6dlv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dlv RCSB], [https://www.ebi.ac.uk/pdbsum/6dlv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dlv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dlv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dlv OCA], [http://pdbe.org/6dlv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dlv RCSB], [http://www.ebi.ac.uk/pdbsum/6dlv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dlv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DYN1_HUMAN DYN1_HUMAN]] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.  
[https://www.uniprot.org/uniprot/DYN1_HUMAN DYN1_HUMAN] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Dynamin GTPase]]
[[Category: Homo sapiens]]
[[Category: Canagarajah, B]]
[[Category: Large Structures]]
[[Category: Fang, S]]
[[Category: Canagarajah B]]
[[Category: Hinshaw, J E]]
[[Category: Fang S]]
[[Category: Kehr, A D]]
[[Category: Hinshaw JE]]
[[Category: Kong, L]]
[[Category: Kehr AD]]
[[Category: Rice, W J]]
[[Category: Kong L]]
[[Category: Wang, H]]
[[Category: Rice WJ]]
[[Category: Dynamin family]]
[[Category: Wang H]]
[[Category: Endocytosis]]
[[Category: Gtpase]]
[[Category: Hydrolase]]
[[Category: Membrane protein]]
[[Category: Pleckstrin homology domain]]

Latest revision as of 17:35, 13 March 2024

Cryo-EM of the GTP-bound human dynamin-1 polymer assembled on the membrane in the super constricted stateCryo-EM of the GTP-bound human dynamin-1 polymer assembled on the membrane in the super constricted state

6dlv, resolution 10.10Å

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