Luciferase: Difference between revisions

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== Relevance ==
== Relevance ==
Luc is used in biological research to assess gene transfection into cells where the Luc gene is added to the transfected gene and the light emission by Luc measured for indication of the transfection success<ref>PMID:3072883</ref>.   
Luc is used in biological research to assess gene transfection into cells where the Luc gene is added to the transfected gene and the light emission by Luc measured for indication of the transfection success<ref>PMID:3072883</ref>.  '''NanoLuc luciferase''' is a small mutated luciferase from shrimp with enhanced stability and a significant increase in luminescence <ref>PMID:27045664</ref>.
</StructureSection>


== 3D Structures of Luciferase ==
== 3D Structures of Luciferase ==
[[Luciferase 3D structures]]


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
</StructureSection>
{{#tree:id=OrganizedByTopic|openlevels=0|
 
* Luciferase
 
**[[1ba3]] – fLuc+bromoform - firefly<br />
**[[3qya]] – LtLuc (mutant) – ''Lampyris turkestanicus''<br />
**[[4m46]] – LtLuc<br />
**[[3fgc]] – VhLuc α+β chain+FMN – ''Vibrio harveyi''<br />
**[[1luc]], [[1brl]] - VhLuc α+β chain<br />
**[[1bsl]], [[1xkj]] - VhLuc β chain<br />
 
*Luciferin 2-monooxygenase
 
**[[2psd]], [[2psh]], [[2psj]], [[2pse]], [[2psf]] – Luc (mutant) – ''Renilla reniformis''<br />
**[[5b0u]] – Luc (mutant) catalytic subunit – luminous shrimp<br />
 
*Luciferin 4-monooxygenase
 
**[[3iep]], [[1lci]], [[5dv9]], [[3ier]] – fLuc <br />
**[[5kyt]], [[5kyv]] – fLuc (mutant)<br />
**[[5dwv]] – fLuc+ substrate analog<br />
**[[3ies]], [[3rix]], [[4e5d]] – fLuc+inhibitor<br />
**[[4g36]] – fLUc + dehydroluciferyl-sulfamoyl adenosine<br />
**[[4g37]] – fLUc (mutant) + dehydroluciferyl-sulfamoyl adenosine<br />
**[[5gz2]] – fLuc + thiazole derivative<br />
**[[5gyz]] – fLuc + AMP + thiazole derivative<br />
**[[5wys]] – fLuc + inhibitor<br />
**[[2d1q]] – LcLuc (mutant)+MgATP – ''Luciola cruciata''<br />
**[[2d1r]] - LcLuc (mutant)+oxyluciferin+AMP<br />
**[[2d1s]], [[2d1t]] - LcLuc (mutant)+intermediate analog<br />
**[[2psd]], [[2psh]], [[2psj]], [[2pse]], [[2psf]] – Luc (mutant) – ''Renilla reniformis''<br />
}}
 


==Additional information==
==Additional information==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur, David Canner, Loïc Gazquez, Alexander Berchansky, Michal Harel, Charlene Planchenault