6a96: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 6a96 is ON HOLD
+==Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25==
+<SX load='6a96' size='340' side='right' viewer='molstar' caption='[[6a96]], [[Resolution|resolution]] 3.51&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6a96]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A96 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.51&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABU:GAMMA-AMINO-BUTANOIC+ACID'>ABU</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a96 OCA], [https://pdbe.org/6a96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a96 RCSB], [https://www.ebi.ac.uk/pdbsum/6a96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a96 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GBRA5_HUMAN GBRA5_HUMAN] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
-Authors: Liu, S., Xu, L., Guan, F., Liu, Y.T., Cui, Y., Zhang, Q., Bi, G.Q., Zhou, Z.H., Zhang, X., Ye, S.
+==See Also==
+*[[GABA receptor 3D structures|GABA receptor 3D structures]]
-Description: Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25
+__TOC__
-[[Category: Unreleased Structures]]
+</SX>
-[[Category: Bi, G.Q]]
+[[Category: Homo sapiens]]
-[[Category: Ye, S]]
+[[Category: Lama glama]]
-[[Category: Zhou, Z.H]]
+[[Category: Large Structures]]
-[[Category: Cui, Y]]
+[[Category: Bi GQ]]
-[[Category: Guan, F]]
+[[Category: Cui Y]]
-[[Category: Liu, S]]
+[[Category: Guan F]]
-[[Category: Xu, L]]
+[[Category: Liu S]]
-[[Category: Liu, Y.T]]
+[[Category: Liu YT]]
-[[Category: Zhang, X]]
+[[Category: Xu L]]
-[[Category: Zhang, Q]]
+[[Category: Ye S]]
+[[Category: Zhang Q]]
+[[Category: Zhang X]]
+[[Category: Zhou ZH]]