Kisker lab: 5B5Q: Difference between revisions
No edit summary |
|||
| (2 intermediate revisions by the same user not shown) | |||
| Line 60: | Line 60: | ||
===Substrate binding site=== | ===Substrate binding site=== | ||
Before you look at the shape of the binding site of Cdu1, you probably will want to show the overall view of again: <scene name='78/781027/Panela/3'>Panel A</scene>. | |||
<scene name='78/781027/Bonus/5'>Bonus figure:</scene> The active-site cysteine sidechain acting as a nucleophile in the hydrolysis reaction is buried surprisingly deeply, barely visible in the surface view (yellow). The alpha helix inserted between strand 1 and | <scene name='78/781027/Bonus/5'>Bonus figure:</scene> The active-site cysteine sidechain acting as a nucleophile in the hydrolysis reaction is buried surprisingly deeply, barely visible in the surface view (yellow patches on the gray surface). The alpha helix (also shown in yellow) inserted between strand 1 and 2 is above the substrate binding cavity, with Val 271 blocking access to the active site. | ||
</StructureSection> | </StructureSection> | ||