2ga5: Difference between revisions
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==yeast frataxin== | ==yeast frataxin== | ||
<StructureSection load='2ga5' size='340' side='right' caption='[[2ga5 | <StructureSection load='2ga5' size='340' side='right'caption='[[2ga5]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ga5]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2ga5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1xaq 1xaq]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GA5 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ga5 OCA], [https://pdbe.org/2ga5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ga5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ga5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ga5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/FRDA_YEAST FRDA_YEAST] Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. Plays a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). Can store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. May be involved in regulation of the mitochondrial electron transport chain.<ref>PMID:9180083</ref> <ref>PMID:9988680</ref> <ref>PMID:15961414</ref> <ref>PMID:16371422</ref> <ref>PMID:19884169</ref> <ref>PMID:17027502</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 2ga5" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2ga5" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Frataxin 3D Structures|Frataxin 3D Structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Alam | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Dancis | [[Category: Alam SL]] | ||
[[Category: He | [[Category: Dancis A]] | ||
[[Category: Lesuisse | [[Category: He Y]] | ||
[[Category: Proteasa | [[Category: Lesuisse E]] | ||
[[Category: Zhang | [[Category: Proteasa SV]] | ||
[[Category: Zhang Y]] | |||