2ga5: Difference between revisions

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==yeast frataxin==
==yeast frataxin==
<StructureSection load='2ga5' size='340' side='right' caption='[[2ga5]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2ga5' size='340' side='right'caption='[[2ga5]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ga5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1xaq 1xaq]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GA5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GA5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ga5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1xaq 1xaq]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GA5 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YFH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ga5 OCA], [http://pdbe.org/2ga5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ga5 RCSB], [http://www.ebi.ac.uk/pdbsum/2ga5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ga5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ga5 OCA], [https://pdbe.org/2ga5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ga5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ga5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ga5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FRDA_YEAST FRDA_YEAST]] Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. Plays a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). Can store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. May be involved in regulation of the mitochondrial electron transport chain.<ref>PMID:9180083</ref> <ref>PMID:9988680</ref> <ref>PMID:15961414</ref> <ref>PMID:16371422</ref> <ref>PMID:19884169</ref> <ref>PMID:17027502</ref>
[https://www.uniprot.org/uniprot/FRDA_YEAST FRDA_YEAST] Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. Plays a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). Can store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. May be involved in regulation of the mitochondrial electron transport chain.<ref>PMID:9180083</ref> <ref>PMID:9988680</ref> <ref>PMID:15961414</ref> <ref>PMID:16371422</ref> <ref>PMID:19884169</ref> <ref>PMID:17027502</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 2ga5" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2ga5" style="background-color:#fffaf0;"></div>
==See Also==
*[[Frataxin 3D Structures|Frataxin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Alam, S L]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Dancis, A]]
[[Category: Alam SL]]
[[Category: He, Y]]
[[Category: Dancis A]]
[[Category: Lesuisse, E]]
[[Category: He Y]]
[[Category: Proteasa, S V]]
[[Category: Lesuisse E]]
[[Category: Zhang, Y]]
[[Category: Proteasa SV]]
[[Category: Chaperone]]
[[Category: Zhang Y]]
[[Category: Yfh1]]

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