6ejm: Difference between revisions

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 ==CRYSTAL STRUCTURE OF HUMAN CD81 LARGE EXTRACELLULAR LOOP IN COMPLEX WITH SINGLE CHAIN FV FRAGMENT 5==
-<StructureSection load='6ejm' size='340' side='right' caption='[[6ejm]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
+<StructureSection load='6ejm' size='340' side='right'caption='[[6ejm]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6ejm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EJM FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6ejm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EJM FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dfw|5dfw]], [[6ejg|6ejg]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD81, TAPA1, TSPAN28 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ejm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ejm OCA], [https://pdbe.org/6ejm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ejm RCSB], [https://www.ebi.ac.uk/pdbsum/6ejm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ejm ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ejm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ejm OCA], [http://pdbe.org/6ejm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ejm RCSB], [http://www.ebi.ac.uk/pdbsum/6ejm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ejm ProSAT]</span></td></tr>
 </table>
-== Disease ==
-[[http://www.uniprot.org/uniprot/CD81_HUMAN CD81_HUMAN]] Defects in CD81 are the cause of immunodeficiency common variable type 6 (CVID6) [MIM:[http://omim.org/entry/613496 613496]]; also called antibody deficiency due to CD81 defect. CVID6 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low.<ref>PMID:20237408</ref>
-== Function ==
-[[http://www.uniprot.org/uniprot/CD81_HUMAN CD81_HUMAN]] May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 21: / Line 16: @@
 </div>
 <div class="pdbe-citations 6ejm" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Antibody 3D structures|Antibody 3D structures]]
+*[[CD81|CD81]]
+*[[3D structures of non-human antibody|3D structures of non-human antibody]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Lk3 transgenic mice]]
+[[Category: Large Structures]]
-[[Category: Harris, S F]]
+[[Category: Mus musculus]]
-[[Category: Kuglstatter, A]]
+[[Category: Harris SF]]
-[[Category: Villasenor, A]]
+[[Category: Kuglstatter A]]
-[[Category: Antibody-antigen complex]]
+[[Category: Villasenor A]]
-[[Category: Cell adhesion]]
-[[Category: Helical bundle]]