5zk0: Difference between revisions

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==Crystal structure of Peptidyl-tRNA hydrolase mutant -M71A from Vibrio cholerae==
==Crystal structure of Peptidyl-tRNA hydrolase mutant -M71A from Vibrio cholerae==
<StructureSection load='5zk0' size='340' side='right' caption='[[5zk0]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='5zk0' size='340' side='right'caption='[[5zk0]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5zk0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibch Vibch]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5h6f 5h6f]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZK0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5zk0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5h6f 5h6f]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZK0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=2CO:S-HYDROPEROXYCYSTEINE'>2CO</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2CO:S-HYDROPEROXYCYSTEINE'>2CO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pth, VC_2184 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243277 VIBCH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zk0 OCA], [https://pdbe.org/5zk0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zk0 RCSB], [https://www.ebi.ac.uk/pdbsum/5zk0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zk0 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zk0 OCA], [http://pdbe.org/5zk0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zk0 RCSB], [http://www.ebi.ac.uk/pdbsum/5zk0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zk0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PTH_VIBCH PTH_VIBCH]] The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.  
[https://www.uniprot.org/uniprot/PTH_VIBCH PTH_VIBCH] The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Serpin|Serpin]]
*[[Peptidyl-tRNA hydrolase|Peptidyl-tRNA hydrolase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aminoacyl-tRNA hydrolase]]
[[Category: Large Structures]]
[[Category: Vibch]]
[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
[[Category: Arora, A]]
[[Category: Arora A]]
[[Category: Kabra, A]]
[[Category: Kabra A]]
[[Category: Pal, R K]]
[[Category: Pal RK]]
[[Category: Shahid, S]]
[[Category: Shahid S]]
[[Category: Hydrolase]]
[[Category: Mutant m71a]]
[[Category: Peptidyl-trna hydrolase]]

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