2e4z: Difference between revisions

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OCA

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 ==Crystal structure of the ligand-binding region of the group III metabotropic glutamate receptor==
-<StructureSection load='2e4z' size='340' side='right' caption='[[2e4z]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
+<StructureSection load='2e4z' size='340' side='right'caption='[[2e4z]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2e4z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E4Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E4Z FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2e4z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E4Z FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2e4u|2e4u]], [[2e4v|2e4v]], [[2e4w|2e4w]], [[2e4x|2e4x]], [[2e4y|2e4y]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e4z OCA], [http://pdbe.org/2e4z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e4z RCSB], [http://www.ebi.ac.uk/pdbsum/2e4z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2e4z ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e4z OCA], [https://pdbe.org/2e4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e4z RCSB], [https://www.ebi.ac.uk/pdbsum/2e4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e4z ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/GRM7_RAT GRM7_RAT]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<ref>PMID:8145723</ref> <ref>PMID:8288585</ref>
+[https://www.uniprot.org/uniprot/GRM7_RAT GRM7_RAT] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<ref>PMID:8145723</ref> <ref>PMID:8288585</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 15: / Line 15: @@
    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e4/2e4z_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 31: / Line 31: @@
 ==See Also==
-*[[Metabotropic glutamate receptor|Metabotropic glutamate receptor]]
+*[[Metabotropic glutamate receptor 3D structures|Metabotropic glutamate receptor 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Buffalo rat]]
+[[Category: Large Structures]]
-[[Category: Jingami, H]]
+[[Category: Rattus norvegicus]]
-[[Category: Morikawa, K]]
+[[Category: Jingami H]]
-[[Category: Muto, T]]
+[[Category: Morikawa K]]
-[[Category: Tsuchiya, D]]
+[[Category: Muto T]]
-[[Category: Central nerve system]]
+[[Category: Tsuchiya D]]
-[[Category: G-protein-coupled receptor]]
-[[Category: Neuron]]
-[[Category: Signaling protein]]