5yki: Difference between revisions
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==Crystal structure of the engineered nine-repeat PUF domain in complex with cognate 9nt-RNA== | ==Crystal structure of the engineered nine-repeat PUF domain in complex with cognate 9nt-RNA== | ||
<StructureSection load='5yki' size='340' side='right' caption='[[5yki]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='5yki' size='340' side='right'caption='[[5yki]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5yki]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5yki]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YKI FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yki OCA], [https://pdbe.org/5yki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yki RCSB], [https://www.ebi.ac.uk/pdbsum/5yki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yki ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PUM1_HUMAN PUM1_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Synthetic construct]] | ||
[[Category: | [[Category: Li HT]] | ||
[[Category: | [[Category: Wang J]] | ||
[[Category: | [[Category: Wang ZX]] | ||
[[Category: | [[Category: Wu JW]] | ||
[[Category: | [[Category: Zhao YY]] | ||