Flavin reductase: Difference between revisions
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== Structural insights == | == Structural insights == | ||
The <scene name='49/490853/Cv/ | The <scene name='49/490853/Cv/4'>NADP containing active site can accommodate a variety of ligands</scene> because the binding is achieved mainly via hydrophobic interactions ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}).<ref>PMID:11224564</ref> | ||
</StructureSection> | </StructureSection> | ||
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
*NADPH-dependent Flavin reductase | *NADPH-dependent Flavin reductase or biliverdin IX beta reductase | ||
**[[ | **[[1hdo]], [[7er6]] - hFR + NADP - human<br /> | ||
**[[6opl]] – hFR (mutant) + NADP <br /> | |||
**[[ | |||
**[[1he2]] - hFR + biliverdin IX α + NADP<BR /> | **[[1he2]] - hFR + biliverdin IX α + NADP<BR /> | ||
**[[1he3]] - hFR + mesobiliverdin IV α + NADP<BR /> | **[[1he3]] - hFR + mesobiliverdin IV α + NADP<BR /> | ||
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**[[5ooh]] – hFR + NADP + erythrosine<br /> | **[[5ooh]] – hFR + NADP + erythrosine<br /> | ||
**[[5oog]] – hFR + NADP + phloxine + cyanosine<br /> | **[[5oog]] – hFR + NADP + phloxine + cyanosine<br /> | ||
**[[7er7]], [[7er8]], [[7er9]], [[7era]], [[7erb]], [[7erc]], [[7erd]], [[7ere]] – hFR + NADP + drug<br /> | |||
**[[3pft]] - FR (mutant) + FMN – ''Mycobacterium goodii''<br /> | **[[3pft]] - FR (mutant) + FMN – ''Mycobacterium goodii''<br /> | ||
**[[5cho]] - FR + FAD – uncultured bacteria<br /> | **[[5cho]] - FR + FAD – uncultured bacteria<br /> | ||
**[[1qfj]] – FR – ''Escherichia coli''<br /> | |||
**[[1bkj]] – VhFR + FMN – ''Vibrio harveyi''<br /> | |||
**[[2bkj]] - VhFR + NAD + FMN<br /> | |||
*NADH-dependent Flavin reductase | *NADH-dependent Flavin reductase | ||
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**[[4uth]] - PpFR (mutant) + FMN <br /> | **[[4uth]] - PpFR (mutant) + FMN <br /> | ||
**[[5lnj]], [[5lni]], [[4uti]], [[4utj]] - PpFR (mutant) + FMN derivative + coumarin derivative<br /> | **[[5lnj]], [[5lni]], [[4uti]], [[4utj]] - PpFR (mutant) + FMN derivative + coumarin derivative<br /> | ||
**[[2d36]] - StFR + FMN – ''Sulfurisphaera tokodaii''<br /> | |||
**[[2d37]] - StFR + FMN + NAD<br /> | |||
**[[2d38]] - StFR + FMN + NADP<br /> | |||
}} | }} | ||