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==Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with an analog of seryladenylate==
==Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with an analog of seryladenylate==
<StructureSection load='2cj9' size='340' side='right' caption='[[2cj9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2cj9' size='340' side='right'caption='[[2cj9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cj9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Metbf Metbf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CJ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CJ9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cj9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_barkeri_str._Fusaro Methanosarcina barkeri str. Fusaro]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CJ9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SSA:5-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE'>SSA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cim|2cim]], [[2cja|2cja]], [[2cjb|2cjb]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SSA:5-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE'>SSA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Serine--tRNA_ligase Serine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.11 6.1.1.11] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cj9 OCA], [https://pdbe.org/2cj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cj9 RCSB], [https://www.ebi.ac.uk/pdbsum/2cj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cj9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cj9 OCA], [http://pdbe.org/2cj9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cj9 RCSB], [http://www.ebi.ac.uk/pdbsum/2cj9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cj9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYS2_METBF SYS2_METBF] Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).<ref>PMID:15364939</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Metbf]]
[[Category: Large Structures]]
[[Category: Serine--tRNA ligase]]
[[Category: Methanosarcina barkeri str. Fusaro]]
[[Category: Ahel, D]]
[[Category: Ahel D]]
[[Category: Ban, N]]
[[Category: Ban N]]
[[Category: Bilokapic, S]]
[[Category: Bilokapic S]]
[[Category: Gruic-Sovulj, I]]
[[Category: Gruic-Sovulj I]]
[[Category: Maier, T]]
[[Category: Maier T]]
[[Category: Soll, D]]
[[Category: Soll D]]
[[Category: Weygand-Durasevic, I]]
[[Category: Weygand-Durasevic I]]
[[Category: Ligase]]
[[Category: Seryladenylate]]
[[Category: Trna synthetase]]
[[Category: Zinc ion]]

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