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==Crystal structure of TREX1 in complex with a inosine contained dsDNA==
==Crystal structure of TREX1 in complex with a inosine contained dsDNA==
<StructureSection load='5ywu' size='340' side='right' caption='[[5ywu]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
<StructureSection load='5ywu' size='340' side='right'caption='[[5ywu]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ywu]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YWU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YWU FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ywu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YWU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DI:2-DEOXYINOSINE-5-MONOPHOSPHATE'>DI</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exodeoxyribonuclease_III Exodeoxyribonuclease III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.2 3.1.11.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ywu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ywu OCA], [https://pdbe.org/5ywu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ywu RCSB], [https://www.ebi.ac.uk/pdbsum/5ywu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ywu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ywu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ywu OCA], [http://pdbe.org/5ywu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ywu RCSB], [http://www.ebi.ac.uk/pdbsum/5ywu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ywu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TREX1_MOUSE TREX1_MOUSE]] Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair.<ref>PMID:10391904</ref> <ref>PMID:11279105</ref>
[https://www.uniprot.org/uniprot/TREX1_MOUSE TREX1_MOUSE] Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair.<ref>PMID:10391904</ref> <ref>PMID:11279105</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5ywu" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ywu" style="background-color:#fffaf0;"></div>
==See Also==
*[[Exonuclease 3D structures|Exonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Exodeoxyribonuclease III]]
[[Category: Homo sapiens]]
[[Category: Hsiao, Y Y]]
[[Category: Large Structures]]
[[Category: Deddh family]]
[[Category: Mus musculus]]
[[Category: Dna binding protein-dna complex]]
[[Category: Hsiao YY]]
[[Category: Exonuclease]]
[[Category: Protein-dna complex]]

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