2a68: Difference between revisions
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==Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin== | ==Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin== | ||
<StructureSection load='2a68' size='340' side='right' caption='[[2a68]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='2a68' size='340' side='right'caption='[[2a68]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2a68]] is a 12 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2a68]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A68 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RBT:RIFABUTIN'>RBT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a68 OCA], [https://pdbe.org/2a68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a68 RCSB], [https://www.ebi.ac.uk/pdbsum/2a68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a68 ProSAT], [https://www.topsan.org/Proteins/RSGI/2a68 TOPSAN]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/RPOA_THET8 RPOA_THET8] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[RNA polymerase|RNA polymerase]] | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | ||
*[[Sigma factor|Sigma factor]] | *[[Sigma factor 3D structures|Sigma factor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
[[Category: Artsimovitch | [[Category: Artsimovitch I]] | ||
[[Category: Igarashi | [[Category: Igarashi N]] | ||
[[Category: Matsugaki | [[Category: Matsugaki N]] | ||
[[Category: Perederina | [[Category: Perederina A]] | ||
[[Category: Svetlov D]] | |||
[[Category: Svetlov | [[Category: Svetlov V]] | ||
[[Category: Svetlov | [[Category: Tahirov TH]] | ||
[[Category: Tahirov | [[Category: Vassylyev DG]] | ||
[[Category: Vassylyev | [[Category: Vassylyeva MN]] | ||
[[Category: Vassylyeva | [[Category: Wakatsuki S]] | ||
[[Category: Wakatsuki | |||