4b1f: Difference between revisions

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 ==Design of Inhibitors of Helicobacter pylori Glutamate Racemase as Selective Antibacterial Agents: Incorporation of Imidazoles onto a Core Pyrazolopyrimidinedione Scaffold to Improve Bioavailabilty==
-<StructureSection load='4b1f' size='340' side='right' caption='[[4b1f]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
+<StructureSection load='4b1f' size='340' side='right'caption='[[4b1f]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4b1f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B1F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B1F FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4b1f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B1F FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=KRH:5-METHYL-3-(1-METHYL-1H-IMIDAZOL-5-YL)-7-(2-METHYLPROPYL)-2-(NAPHTHALEN-1-YLMETHYL)-2H-PYRAZOLO[3,4-D]PYRIMIDINE-4,6(5H,7H)-DIONE'>KRH</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jfx|2jfx]], [[2jfy|2jfy]], [[2jfz|2jfz]], [[2w4i|2w4i]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=KRH:5-METHYL-3-(1-METHYL-1H-IMIDAZOL-5-YL)-7-(2-METHYLPROPYL)-2-(NAPHTHALEN-1-YLMETHYL)-2H-PYRAZOLO[3,4-D]PYRIMIDINE-4,6(5H,7H)-DIONE'>KRH</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_racemase Glutamate racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.3 5.1.1.3] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b1f OCA], [https://pdbe.org/4b1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b1f RCSB], [https://www.ebi.ac.uk/pdbsum/4b1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b1f ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b1f OCA], [http://pdbe.org/4b1f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b1f RCSB], [http://www.ebi.ac.uk/pdbsum/4b1f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b1f ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/MURI_HELPJ MURI_HELPJ]] Provides the (R)-glutamate required for cell wall biosynthesis (By similarity).
+[https://www.uniprot.org/uniprot/MURI_HELPJ MURI_HELPJ] Provides the (R)-glutamate required for cell wall biosynthesis (By similarity).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 20: / Line 19: @@
 </div>
 <div class="pdbe-citations 4b1f" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Glutamate racemase 3D structures|Glutamate racemase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Atcc 43504]]
+[[Category: Helicobacter pylori]]
-[[Category: Glutamate racemase]]
+[[Category: Large Structures]]
-[[Category: Basarab, G S]]
+[[Category: Basarab GS]]
-[[Category: Eyermann, C J]]
+[[Category: Eyermann CJ]]
-[[Category: Gowravaram, M]]
+[[Category: Gowravaram M]]
-[[Category: Hill, P]]
+[[Category: Hill P]]
-[[Category: Kack, H]]
+[[Category: Kack H]]
-[[Category: Osimoni, E]]
+[[Category: Osimoni E]]
-[[Category: Improved bioavailability]]
-[[Category: Isomerase]]