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==Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB).==
==Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB).==
<StructureSection load='4wvg' size='340' side='right' caption='[[4wvg]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='4wvg' size='340' side='right'caption='[[4wvg]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4wvg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Eco57 Eco57]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WVG FirstGlance]. <br>
<table><tr><td colspan='2'>[[4wvg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._Newman Staphylococcus aureus subsp. aureus str. Newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WVG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAL:MALTOSE'>MAL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wvj|4wvj]], [[4wvi|4wvi]], [[4wvh|4wvh]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">spsB, SACOL0969 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83334 ECO57])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wvg OCA], [https://pdbe.org/4wvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wvg RCSB], [https://www.ebi.ac.uk/pdbsum/4wvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wvg ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Signal_peptidase_I Signal peptidase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.89 3.4.21.89] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wvg OCA], [http://pdbe.org/4wvg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wvg RCSB], [http://www.ebi.ac.uk/pdbsum/4wvg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wvg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MALE_ECO57 MALE_ECO57]] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides (By similarity).  
[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/LEP_STAAC LEP_STAAC] Essential for cell viability.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Eco57]]
[[Category: Escherichia coli K-12]]
[[Category: Signal peptidase I]]
[[Category: Large Structures]]
[[Category: Baker, E N]]
[[Category: Staphylococcus aureus subsp. aureus str. Newman]]
[[Category: Ting, Y T]]
[[Category: Baker EN]]
[[Category: Young, P G]]
[[Category: Ting YT]]
[[Category: Cell secretion]]
[[Category: Young PG]]
[[Category: Hydrolase]]
[[Category: Mbp fusion protein]]
[[Category: Spsb type-i signal peptidase]]

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