6brf: Difference between revisions

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-'''Unreleased structure'''
-The entry 6brf is ON HOLD  until Paper Publication
+==Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 4b==
+<StructureSection load='6brf' size='340' side='right'caption='[[6brf]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6brf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BRF FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=E44:2-chloro-4-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)pyrido[3,2-d]pyrimidine'>E44</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6brf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6brf OCA], [https://pdbe.org/6brf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6brf RCSB], [https://www.ebi.ac.uk/pdbsum/6brf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6brf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
-Authors: Kumar, G., Wang, Y., Li, W., White, S.W.
+==See Also==
+*[[Stathmin-4 3D structures|Stathmin-4 3D structures]]
-Description: Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 4b
+*[[Tubulin 3D Structures|Tubulin 3D Structures]]
-[[Category: Unreleased Structures]]
+*[[Tubulin tyrosine ligase 3D structures|Tubulin tyrosine ligase 3D structures]]
-[[Category: White, S.W]]
+__TOC__
-[[Category: Kumar, G]]
+</StructureSection>
-[[Category: Wang, Y]]
+[[Category: Gallus gallus]]
-[[Category: Li, W]]
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Sus scrofa]]
+[[Category: Kumar G]]
+[[Category: Li W]]
+[[Category: Wang Y]]
+[[Category: White SW]]