2gqp: Difference between revisions

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-[[Image:2gqp.jpg|left|200px]]
- {{Structure
+==N-Domain Of Grp94 In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine==
-|PDB= 2gqp |SIZE=350|CAPTION= <scene name='initialview01'>2gqp</scene>, resolution 1.50&Aring;
+<StructureSection load='2gqp' size='340' side='right'caption='[[2gqp]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=MO6:MAGNESIUM+ION,+6+WATERS+COORDINATED'>MO6</scene>, <scene name='pdbligand=PA7:N-PROPYL+CARBOXYAMIDO+ADENOSINE'>PA7</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>
+<table><tr><td colspan='2'>[[2gqp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GQP FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
-|GENE= HSP90B1, TRA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 Canis lupus familiaris])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PA7:N-PROPYL+CARBOXYAMIDO+ADENOSINE'>PA7</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
-|DOMAIN=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gqp OCA], [https://pdbe.org/2gqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gqp RCSB], [https://www.ebi.ac.uk/pdbsum/2gqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gqp ProSAT]</span></td></tr>
-|RELATEDENTRY=[[1u0y|1U0Y]], [[1u2o|1U2O]], [[1yt1|1YT1]]
+</table>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gqp OCA], [http://www.ebi.ac.uk/pdbsum/2gqp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2gqp RCSB]</span>
+== Function ==
-}}
+[https://www.uniprot.org/uniprot/ENPL_CANLF ENPL_CANLF] Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/2gqp_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gqp ConSurf].
+<div style="clear:both"></div>
-'''N-Domain Of Grp94 In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine'''
+==See Also==
+*[[Heat Shock Protein structures|Heat Shock Protein structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-GQP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQP OCA].
 [[Category: Canis lupus familiaris]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Gewirth, D T.]]
+[[Category: Gewirth DT]]
-[[Category: Immormino, R M.]]
+[[Category: Immormino RM]]
-[[Category: adenosine]]
-[[Category: chaperone]]
-[[Category: grp94]]
-[[Category: hsp82]]
-[[Category: hsp90]]
-[[Category: htpg]]
-[[Category: ligand]]
-[[Category: neca]]
-[[Category: npca]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:20:12 2008''