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==Crystal Structure Analysis of FGF2-Disaccharide (S3I2) complex==
==Crystal Structure Analysis of FGF2-Disaccharide (S3I2) complex==
<StructureSection load='4oee' size='340' side='right' caption='[[4oee]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='4oee' size='340' side='right'caption='[[4oee]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4oee]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OEE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OEE FirstGlance]. <br>
<table><tr><td colspan='2'>[[4oee]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OEE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNX:2-DEOXY-3-O-SULFO-2-(SULFOAMINO)-ALPHA-D-GLUCOPYRANOSE'>GNX</scene>, <scene name='pdbligand=IDY:METHYL+2-O-SULFO-ALPHA-L-IDOPYRANOSIDURONIC+ACID'>IDY</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4oef|4oef]], [[4oeg|4oeg]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNX:2-DEOXY-3-O-SULFO-2-(SULFOAMINO)-ALPHA-D-GLUCOPYRANOSE'>GNX</scene>, <scene name='pdbligand=IDY:METHYL+2-O-SULFO-ALPHA-L-IDOPYRANOSIDURONIC+ACID'>IDY</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FGF2, FGFB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oee OCA], [https://pdbe.org/4oee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oee RCSB], [https://www.ebi.ac.uk/pdbsum/4oee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oee ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oee OCA], [http://pdbe.org/4oee PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4oee RCSB], [http://www.ebi.ac.uk/pdbsum/4oee PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4oee ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FGF2_HUMAN FGF2_HUMAN]] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:1721615</ref> <ref>PMID:8663044</ref>
[https://www.uniprot.org/uniprot/FGF2_HUMAN FGF2_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:1721615</ref> <ref>PMID:8663044</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Fibroblast growth factor|Fibroblast growth factor]]
*[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Hsiao, C D]]
[[Category: Large Structures]]
[[Category: Li, Y C]]
[[Category: Hsiao CD]]
[[Category: Heparin/heparin sulfate binding]]
[[Category: Li YC]]
[[Category: Protein binding]]

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