1tej: Difference between revisions

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==Crystal structure of a disintegrin heterodimer at 1.9 A resolution.==
==Crystal structure of a disintegrin heterodimer at 1.9 A resolution.==
<StructureSection load='1tej' size='340' side='right' caption='[[1tej]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1tej' size='340' side='right'caption='[[1tej]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1tej]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TEJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TEJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1tej]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TEJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TEJ FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tej OCA], [http://pdbe.org/1tej PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tej RCSB], [http://www.ebi.ac.uk/pdbsum/1tej PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tej ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tej OCA], [https://pdbe.org/1tej PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tej RCSB], [https://www.ebi.ac.uk/pdbsum/1tej PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tej ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DIDS_ECHCA DIDS_ECHCA]] May bind to both alpha-IIb/beta-3 (ITGA2B/ITGB3) and alpha-V/beta-3 (ITGAV/ITGB3) integrins, and may inhibit platelet aggregation.
[https://www.uniprot.org/uniprot/DIDLA_ECHCA DIDLA_ECHCA]  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Echis carinatus]]
[[Category: Echis carinatus]]
[[Category: Betzel, C]]
[[Category: Large Structures]]
[[Category: Bilgrami, S]]
[[Category: Betzel C]]
[[Category: Kaur, P]]
[[Category: Bilgrami S]]
[[Category: Perbandt, M]]
[[Category: Kaur P]]
[[Category: Singh, T P]]
[[Category: Perbandt M]]
[[Category: Yadav, S]]
[[Category: Singh TP]]
[[Category: Cryatal structure]]
[[Category: Yadav S]]
[[Category: Disintegrin]]
[[Category: Heterodimer]]
[[Category: Protein binding]]

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