6ftt: Difference between revisions
Jump to navigation
Jump to search
m Protected "6ftt" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
==ATP phosphoribosyltransferase (HisZG ATPPRT) from Psychrobacter arcticus in complex with PRPP== | |||
<StructureSection load='6ftt' size='340' side='right' caption='[[6ftt]], [[Resolution|resolution]] 2.29Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ftt]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FTT FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ATP_phosphoribosyltransferase ATP phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.17 2.4.2.17] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ftt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ftt OCA], [http://pdbe.org/6ftt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ftt RCSB], [http://www.ebi.ac.uk/pdbsum/6ftt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ftt ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/HISZ_PSYA2 HISZ_PSYA2]] Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.[HAMAP-Rule:MF_00125] [[http://www.uniprot.org/uniprot/HIS1_PSYA2 HIS1_PSYA2]] Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: ATP phosphoribosyltransferase]] | |||
[[Category: Alphey, M S]] | |||
[[Category: Czekster, C M]] | |||
[[Category: Fisher, G]] | |||
[[Category: Ge, Y]] | |||
[[Category: Naismith, J H]] | |||
[[Category: Silva, R G.da]] | |||
[[Category: Atp phosphoribosyltransferase]] | |||
[[Category: Cold-adapted]] | |||
[[Category: Hiszg]] | |||
[[Category: Transferase]] | |||
Latest revision as of 08:57, 24 October 2018
ATP phosphoribosyltransferase (HisZG ATPPRT) from Psychrobacter arcticus in complex with PRPPATP phosphoribosyltransferase (HisZG ATPPRT) from Psychrobacter arcticus in complex with PRPP
Structural highlights
Function[HISZ_PSYA2] Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.[HAMAP-Rule:MF_00125] [HIS1_PSYA2] Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. |
| ||||||||||||||||||