6fn4: Difference between revisions

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==Apo form of UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM)==
==Apo form of UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM)==
<StructureSection load='6fn4' size='340' side='right' caption='[[6fn4]], [[Resolution|resolution]] 4.14&Aring;' scene=''>
<SX load='6fn4' size='340' side='right' viewer='molstar' caption='[[6fn4]], [[Resolution|resolution]] 4.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6fn4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FN4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FN4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6fn4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FN4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3PE:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>3PE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.14&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6fn1|6fn1]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PE:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>3PE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fn4 OCA], [http://pdbe.org/6fn4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fn4 RCSB], [http://www.ebi.ac.uk/pdbsum/6fn4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fn4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fn4 OCA], [https://pdbe.org/6fn4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fn4 RCSB], [https://www.ebi.ac.uk/pdbsum/6fn4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fn4 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/MDR1_HUMAN MDR1_HUMAN] Ulcerative colitis. Disease susceptibility is associated with variations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/MDR1_HUMAN MDR1_HUMAN] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6fn4" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6fn4" style="background-color:#fffaf0;"></div>
==See Also==
*[[Antibody 3D structures|Antibody 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Alam, A]]
[[Category: Mus musculus]]
[[Category: Locher, K P]]
[[Category: Alam A]]
[[Category: Membrane protein]]
[[Category: Locher KP]]
[[Category: Membrane transport protein abcb1 abc exporter small molecule inhibitor antibody complex]]

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