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==CRYSTAL STRUCTURE OF MURD LIGASE FROM ESCHERICHIA COLI==
==CRYSTAL STRUCTURE OF MURD LIGASE FROM ESCHERICHIA COLI==
<StructureSection load='5a5e' size='340' side='right' caption='[[5a5e]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
<StructureSection load='5a5e' size='340' side='right'caption='[[5a5e]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5a5e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A5E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A5E FirstGlance]. <br>
<table><tr><td colspan='2'>[[5a5e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A5E FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a5f|5a5f]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a5e OCA], [https://pdbe.org/5a5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a5e RCSB], [https://www.ebi.ac.uk/pdbsum/5a5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a5e ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a5e OCA], [http://pdbe.org/5a5e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a5e RCSB], [http://www.ebi.ac.uk/pdbsum/5a5e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a5e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI]] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]  
[https://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5a5e" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5a5e" style="background-color:#fffaf0;"></div>
==See Also==
*[[Mur ligase|Mur ligase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]
[[Category: Large Structures]]
[[Category: Barreteau, H]]
[[Category: Barreteau H]]
[[Category: Blanot, D]]
[[Category: Blanot D]]
[[Category: Contreras-Martel, C]]
[[Category: Contreras-Martel C]]
[[Category: Dessen, A]]
[[Category: Dessen A]]
[[Category: Gobec, S]]
[[Category: Gobec S]]
[[Category: Kotnik, M]]
[[Category: Kotnik M]]
[[Category: Sink, R]]
[[Category: Sink R]]
[[Category: Zega, A]]
[[Category: Zega A]]
[[Category: Adp-forming enzyme]]
[[Category: Atp- binding]]
[[Category: Cell cycle]]
[[Category: Cell division]]
[[Category: Cell shape]]
[[Category: Cell wall]]
[[Category: Conformation]]
[[Category: Ligand]]
[[Category: Ligase]]
[[Category: Nucleotide-binding]]
[[Category: Peptidoglycan synthesis]]

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