5qcc: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:


==Crystal structure of human Cathepsin-S with bound ligand==
==Crystal structure of human Cathepsin-S with bound ligand==
<StructureSection load='5qcc' size='340' side='right' caption='[[5qcc]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='5qcc' size='340' side='right'caption='[[5qcc]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5qcc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QCC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QCC FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QCC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGY:tert-butyl+4-(2-{3-(4-chloro-3-iodophenyl)-1-[3-(morpholin-4-yl)propyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}-2-oxoethyl)piperidine-1-carboxylate'>BGY</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGY:tert-butyl+4-(2-{3-(4-chloro-3-iodophenyl)-1-[3-(morpholin-4-yl)propyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}-2-oxoethyl)piperidine-1-carboxylate'>BGY</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qcc OCA], [https://pdbe.org/5qcc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qcc RCSB], [https://www.ebi.ac.uk/pdbsum/5qcc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qcc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qcc OCA], [http://pdbe.org/5qcc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qcc RCSB], [http://www.ebi.ac.uk/pdbsum/5qcc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qcc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
 
[[http://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
==See Also==
*[[Cathepsin 3D structures|Cathepsin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cathepsin S]]
[[Category: Large Structures]]
[[Category: Human]]
[[Category: Ameriks MK]]
[[Category: Ameriks, M K]]
[[Category: Bembenek SD]]
[[Category: Bembenek, S D]]
[[Category: Burley SK]]
[[Category: Burley, S K]]
[[Category: Mirzadegan T]]
[[Category: Mirzadegan, T]]
[[Category: Shao C]]
[[Category: Shao, C]]
[[Category: Yang H]]
[[Category: Yang, H]]
[[Category: Cathepsin s]]
[[Category: D3r]]
[[Category: Hydrolase]]
[[Category: Ligand docking]]

Latest revision as of 07:38, 21 November 2024

Crystal structure of human Cathepsin-S with bound ligandCrystal structure of human Cathepsin-S with bound ligand

Structural highlights

Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

See Also

5qcc, resolution 1.80Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=5qcc&oldid=4220387"