2ept: Difference between revisions

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[[Image:2ept.jpg|left|200px]]


{{Structure
==Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 32==
|PDB= 2ept |SIZE=350|CAPTION= <scene name='initialview01'>2ept</scene>
<StructureSection load='2ept' size='340' side='right'caption='[[2ept]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[2ept]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EPT FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= ZNF32, KOX30 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ept FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ept OCA], [https://pdbe.org/2ept PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ept RCSB], [https://www.ebi.ac.uk/pdbsum/2ept PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ept ProSAT], [https://www.topsan.org/Proteins/RSGI/2ept TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ept FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ept OCA], [http://www.ebi.ac.uk/pdbsum/2ept PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ept RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/ZNF32_HUMAN ZNF32_HUMAN] May be involved in transcriptional regulation.
 
== Evolutionary Conservation ==
'''Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 32'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ep/2ept_consurf.spt"</scriptWhenChecked>
2EPT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPT OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ept ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Muto, Y.]]
[[Category: Muto Y]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Shirouzu M]]
[[Category: Shirouzu, M.]]
[[Category: Suzuki S]]
[[Category: Suzuki, S.]]
[[Category: Tanabe W]]
[[Category: Tanabe, W.]]
[[Category: Terada T]]
[[Category: Terada, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: c2h2]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: transcription]]
[[Category: zinc finger domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:52:20 2008''

Latest revision as of 21:54, 29 May 2024

Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 32Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 32

Structural highlights

2ept is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

ZNF32_HUMAN May be involved in transcriptional regulation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

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