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| [[Image:2ejc.jpg|left|200px]]
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| {{Structure
| | ==Crystal Structure Of Pantoate--Beta-Alanine Ligase (panC) From Thermotoga maritima== |
| |PDB= 2ejc |SIZE=350|CAPTION= <scene name='initialview01'>2ejc</scene>, resolution 2.40Å
| | <StructureSection load='2ejc' size='340' side='right'caption='[[2ejc]], [[Resolution|resolution]] 2.40Å' scene=''> |
| |SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+502'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+A+503'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+A+504'>AC4</scene>, <scene name='pdbsite=AC5:Zn+Binding+Site+For+Residue+A+505'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Residue+A+506'>AC6</scene>, <scene name='pdbsite=AC7:Zn+Binding+Site+For+Residue+A+507'>AC7</scene>, <scene name='pdbsite=AC8:Zn+Binding+Site+For+Residue+A+508'>AC8</scene>, <scene name='pdbsite=AC9:Zn+Binding+Site+For+Residue+A+509'>AC9</scene>, <scene name='pdbsite=BC1:Zn+Binding+Site+For+Residue+A+510'>BC1</scene>, <scene name='pdbsite=BC2:Zn+Binding+Site+For+Residue+A+511'>BC2</scene>, <scene name='pdbsite=BC3:Zn+Binding+Site+For+Residue+A+512'>BC3</scene>, <scene name='pdbsite=BC4:Zn+Binding+Site+For+Residue+A+513'>BC4</scene>, <scene name='pdbsite=BC5:Zn+Binding+Site+For+Residue+A+515'>BC5</scene>, <scene name='pdbsite=BC6:Zn+Binding+Site+For+Residue+A+516'>BC6</scene>, <scene name='pdbsite=BC7:Zn+Binding+Site+For+Residue+A+517'>BC7</scene>, <scene name='pdbsite=BC8:Zn+Binding+Site+For+Residue+A+518'>BC8</scene>, <scene name='pdbsite=BC9:Zn+Binding+Site+For+Residue+A+519'>BC9</scene>, <scene name='pdbsite=CC1:Zn+Binding+Site+For+Residue+A+521'>CC1</scene>, <scene name='pdbsite=CC2:Zn+Binding+Site+For+Residue+A+522'>CC2</scene> and <scene name='pdbsite=CC3:Act+Binding+Site+For+Residue+A+1101'>CC3</scene>
| | == Structural highlights == |
| |LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
| | <table><tr><td colspan='2'>[[2ejc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EJC FirstGlance]. <br> |
| |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span>
| | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> |
| |GENE= panC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])
| | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| |DOMAIN=
| | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ejc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ejc OCA], [https://pdbe.org/2ejc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ejc RCSB], [https://www.ebi.ac.uk/pdbsum/2ejc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ejc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ejc TOPSAN]</span></td></tr> |
| |RELATEDENTRY=
| | </table> |
| |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ejc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ejc OCA], [http://www.ebi.ac.uk/pdbsum/2ejc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ejc RCSB]</span>
| | == Function == |
| }}
| | [https://www.uniprot.org/uniprot/PANC_THEMA PANC_THEMA] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity). |
| | == Evolutionary Conservation == |
| | [[Image:Consurf_key_small.gif|200px|right]] |
| | Check<jmol> |
| | <jmolCheckbox> |
| | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/2ejc_consurf.spt"</scriptWhenChecked> |
| | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| | <text>to colour the structure by Evolutionary Conservation</text> |
| | </jmolCheckbox> |
| | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ejc ConSurf]. |
| | <div style="clear:both"></div> |
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| '''Crystal Structure Of Pantoate--Beta-Alanine Ligase (panC) From Thermotoga maritima'''
| | ==See Also== |
| | | *[[Pantothenate synthetase|Pantothenate synthetase]] |
| | | __TOC__ |
| ==About this Structure== | | </StructureSection> |
| 2EJC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJC OCA].
| | [[Category: Large Structures]] |
| [[Category: Pantoate--beta-alanine ligase]]
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| [[Category: Single protein]] | |
| [[Category: Thermotoga maritima]] | | [[Category: Thermotoga maritima]] |
| [[Category: Bagautdinov, B.]] | | [[Category: Bagautdinov B]] |
| [[Category: Kunishima, N.]] | | [[Category: Kunishima N]] |
| [[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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| [[Category: national project on protein structural and functional analyse]]
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| [[Category: nppsfa]]
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| [[Category: pantoate-beta-alanine ligase]]
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| [[Category: riken structural genomics/proteomics initiative]]
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| [[Category: rsgi]]
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| [[Category: structural genomic]]
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| [[Category: x-ray diffraction]]
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:49:59 2008''
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