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==ROLES OF INDIVIDUAL RESIDUES OF ALPHA-1,3 GALACTOSYLTRANSFERASES IN SUBSTRATE BINDING AND CATALYSIS==
==ROLES OF INDIVIDUAL RESIDUES OF ALPHA-1,3 GALACTOSYLTRANSFERASES IN SUBSTRATE BINDING AND CATALYSIS==
<StructureSection load='1vzt' size='340' side='right' caption='[[1vzt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1vzt' size='340' side='right'caption='[[1vzt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1vzt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1o7r 1o7r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VZT FirstGlance]. <br>
<table><tr><td colspan='2'>[[1vzt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1o7r 1o7r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VZT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fg5|1fg5]], [[1g8o|1g8o]], [[1g93|1g93]], [[1gwv|1gwv]], [[1gww|1gww]], [[1gx0|1gx0]], [[1gx4|1gx4]], [[1k4v|1k4v]], [[1o7o|1o7o]], [[1o7q|1o7q]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzt OCA], [https://pdbe.org/1vzt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vzt RCSB], [https://www.ebi.ac.uk/pdbsum/1vzt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vzt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzt OCA], [http://pdbe.org/1vzt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vzt RCSB], [http://www.ebi.ac.uk/pdbsum/1vzt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vzt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GGTA1_BOVIN GGTA1_BOVIN]] Transfer of galactose from UDP-galactose to an acceptor molecule (R).  
[https://www.uniprot.org/uniprot/GGTA1_BOVIN GGTA1_BOVIN] Transfer of galactose from UDP-galactose to an acceptor molecule (R).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1vzt" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1vzt" style="background-color:#fffaf0;"></div>
==See Also==
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bovin]]
[[Category: Bos taurus]]
[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]
[[Category: Large Structures]]
[[Category: Acharya, K R]]
[[Category: Acharya KR]]
[[Category: Brew, K]]
[[Category: Brew K]]
[[Category: Deshpande, A]]
[[Category: Deshpande A]]
[[Category: Natesh, R]]
[[Category: Natesh R]]
[[Category: Swaminathan, G J]]
[[Category: Swaminathan GJ]]
[[Category: Xie, X]]
[[Category: Xie X]]
[[Category: Zhang, Y]]
[[Category: Zhang Y]]
[[Category: 3-galactosyltransferase-udp complex]]
[[Category: Alpha-1]]
[[Category: Glycoprotein]]
[[Category: Glycosyltransferase]]
[[Category: Nucleotide-binding protein]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Xenotransplantation]]

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