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==Murine Alloreactive ScFv TCR-Peptide-MHC Class I Molecule Complex==
==Murine Alloreactive ScFv TCR-Peptide-MHC Class I Molecule Complex==
<StructureSection load='1kj2' size='340' side='right' caption='[[1kj2]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
<StructureSection load='1kj2' size='340' side='right'caption='[[1kj2]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1kj2]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KJ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KJ2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1kj2]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KJ2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.71&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kj2 OCA], [http://pdbe.org/1kj2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kj2 RCSB], [http://www.ebi.ac.uk/pdbsum/1kj2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kj2 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kj2 OCA], [https://pdbe.org/1kj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kj2 RCSB], [https://www.ebi.ac.uk/pdbsum/1kj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kj2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.  
[https://www.uniprot.org/uniprot/HA1B_MOUSE HA1B_MOUSE] Involved in the presentation of foreign antigens to the immune system.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/1kj2_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/1kj2_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</div>
</div>
<div class="pdbe-citations 1kj2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1kj2" style="background-color:#fffaf0;"></div>
==See Also==
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Darnault, C]]
[[Category: Mus musculus]]
[[Category: Fontecilla-Camps, J C]]
[[Category: Darnault C]]
[[Category: Gregoire, C]]
[[Category: Fontecilla-Camps JC]]
[[Category: Guimezanes, A]]
[[Category: Gregoire C]]
[[Category: Housset, D]]
[[Category: Guimezanes A]]
[[Category: Malissen, B]]
[[Category: Housset D]]
[[Category: Mazza, G]]
[[Category: Malissen B]]
[[Category: Mosser, T]]
[[Category: Mazza G]]
[[Category: Reiser, J B]]
[[Category: Mosser T]]
[[Category: Schmitt-Verhulst, A M]]
[[Category: Reiser J-B]]
[[Category: Allogeneic]]
[[Category: Schmitt-Verhulst A-M]]
[[Category: Class i mhc]]
[[Category: H-2kb]]
[[Category: Immune system]]
[[Category: T cell receptor]]
[[Category: Tcr-pmhc complex]]

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