2drv: Difference between revisions

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[[Image:2drv.gif|left|200px]]


{{Structure
==Structure of PH1069 protein from Pyrococcus horikoshii OT3==
|PDB= 2drv |SIZE=350|CAPTION= <scene name='initialview01'>2drv</scene>, resolution 1.60&Aring;
<StructureSection load='2drv' size='340' side='right'caption='[[2drv]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
<table><tr><td colspan='2'>[[2drv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DRV FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2drv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drv OCA], [https://pdbe.org/2drv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2drv RCSB], [https://www.ebi.ac.uk/pdbsum/2drv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2drv ProSAT], [https://www.topsan.org/Proteins/RSGI/2drv TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2drv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drv OCA], [http://www.ebi.ac.uk/pdbsum/2drv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2drv RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/TYW31_PYRHO TYW31_PYRHO] S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.[HAMAP-Rule:MF_00266]
 
== Evolutionary Conservation ==
'''Structure of PH1069 protein from Pyrococcus horikoshii OT3'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dr/2drv_consurf.spt"</scriptWhenChecked>
2DRV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRV OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Pyrococcus horikoshii]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
[[Category: Kunishima, N.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2drv ConSurf].
[[Category: Lokanath, N K.]]
<div style="clear:both"></div>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
__TOC__
[[Category: hypothetical protein]]
</StructureSection>
[[Category: national project on protein structural and functional analyse]]
[[Category: Large Structures]]
[[Category: nppsfa]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: Kunishima N]]
[[Category: rsgi]]
[[Category: Lokanath NK]]
[[Category: structural genomic]]
[[Category: unknown function]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:38:34 2008''

Latest revision as of 08:10, 17 October 2024

Structure of PH1069 protein from Pyrococcus horikoshii OT3Structure of PH1069 protein from Pyrococcus horikoshii OT3

Structural highlights

2drv is a 2 chain structure with sequence from Pyrococcus horikoshii OT3. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

TYW31_PYRHO S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.[HAMAP-Rule:MF_00266]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2drv, resolution 1.60Å

Drag the structure with the mouse to rotate

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OCA
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