5z2h: Difference between revisions

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New page: '''Unreleased structure''' The entry 5z2h is ON HOLD Authors: OuYang, B., Li, D., Chou, J.J., Yuan, Y., Wen, M. Description: Structure of ddCTD-WT Category: Unreleased Structures [...
 
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'''Unreleased structure'''


The entry 5z2h is ON HOLD
==Structure of Dictyostelium discoideum mitochondrial calcium uniporter N-terminal domain(DdMCU-NTD)==
<StructureSection load='5z2h' size='340' side='right'caption='[[5z2h]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5z2h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z2H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Z2H FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.674&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5z2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z2h OCA], [https://pdbe.org/5z2h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5z2h RCSB], [https://www.ebi.ac.uk/pdbsum/5z2h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5z2h ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MCU_DICDI MCU_DICDI] Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria (PubMed:24889638). Constitutes a pore-forming and calcium-conducting subunit (PubMed:24889638). Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.[UniProtKB:Q8NE86]<ref>PMID:24889638</ref>


Authors: OuYang, B., Li, D., Chou, J.J., Yuan, Y., Wen, M.
==See Also==
 
*[[Mitochondrial calcium uniporter|Mitochondrial calcium uniporter]]
Description: Structure of ddCTD-WT
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Li, D]]
__TOC__
[[Category: Chou, J.J]]
</StructureSection>
[[Category: Wen, M]]
[[Category: Dictyostelium discoideum]]
[[Category: Yuan, Y]]
[[Category: Large Structures]]
[[Category: Ouyang, B]]
[[Category: Bo O]]
[[Category: Chou JJ]]
[[Category: Li D]]
[[Category: Wen M]]
[[Category: Yuan Y]]

Latest revision as of 13:26, 27 March 2024

Structure of Dictyostelium discoideum mitochondrial calcium uniporter N-terminal domain(DdMCU-NTD)Structure of Dictyostelium discoideum mitochondrial calcium uniporter N-terminal domain(DdMCU-NTD)

Structural highlights

5z2h is a 2 chain structure with sequence from Dictyostelium discoideum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.674Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MCU_DICDI Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria (PubMed:24889638). Constitutes a pore-forming and calcium-conducting subunit (PubMed:24889638). Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.[UniProtKB:Q8NE86][1]

See Also

References

  1. Kovacs-Bogdan E, Sancak Y, Kamer KJ, Plovanich M, Jambhekar A, Huber RJ, Myre MA, Blower MD, Mootha VK. Reconstitution of the mitochondrial calcium uniporter in yeast. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8985-90. doi:, 10.1073/pnas.1400514111. Epub 2014 Jun 2. PMID:24889638 doi:http://dx.doi.org/10.1073/pnas.1400514111

5z2h, resolution 1.67Å

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