5z2b: Difference between revisions

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New page: '''Unreleased structure''' The entry 5z2b is ON HOLD Authors: Hibi, T., Itoh, T., Nishiya, Y. Description: Crystal structure of highly active BTUO mutant P287G Improved by Humidity Con...
 
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'''Unreleased structure'''


The entry 5z2b is ON HOLD
==Crystal structure of highly active BTUO mutant P287G Improved by Humidity Control at 86% RH==
 
<StructureSection load='5z2b' size='340' side='right'caption='[[5z2b]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
Authors: Hibi, T., Itoh, T., Nishiya, Y.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5z2b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._TB-90 Bacillus sp. TB-90]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Z2B FirstGlance]. <br>
Description: Crystal structure of highly active BTUO mutant P287G Improved by Humidity Control at 86% RH
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.901&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Itoh, T]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5z2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z2b OCA], [https://pdbe.org/5z2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5z2b RCSB], [https://www.ebi.ac.uk/pdbsum/5z2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5z2b ProSAT]</span></td></tr>
[[Category: Hibi, T]]
</table>
[[Category: Nishiya, Y]]
== Function ==
[https://www.uniprot.org/uniprot/PUCL_BACSB PUCL_BACSB] Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin (By similarity).
__TOC__
</StructureSection>
[[Category: Bacillus sp. TB-90]]
[[Category: Large Structures]]
[[Category: Hibi T]]
[[Category: Itoh T]]
[[Category: Nishiya Y]]

Latest revision as of 11:44, 22 November 2023

Crystal structure of highly active BTUO mutant P287G Improved by Humidity Control at 86% RHCrystal structure of highly active BTUO mutant P287G Improved by Humidity Control at 86% RH

Structural highlights

5z2b is a 2 chain structure with sequence from Bacillus sp. TB-90. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.901Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PUCL_BACSB Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin (By similarity).

5z2b, resolution 1.90Å

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OCA