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==Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid== | |||
<StructureSection load='6f7f' size='340' side='right'caption='[[6f7f]], [[Resolution|resolution]] 2.13Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6f7f]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F7F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F7F FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOP:INDOLYLPROPIONIC+ACID'>IOP</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f7f OCA], [http://pdbe.org/6f7f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f7f RCSB], [http://www.ebi.ac.uk/pdbsum/6f7f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f7f ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Hocker, B]] | |||
[[Category: Shanmugaratnam, S]] | |||
[[Category: Stiel, A C]] | |||
[[Category: Ligand binding]] | |||
[[Category: Transcription]] | |||
Latest revision as of 09:34, 27 March 2019
Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acidTryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid
Structural highlights
Function[TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. |
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