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==Crystal structure of JmjC domain of human histone demethylase UTY in complex with N05859b==
==Crystal structure of JmjC domain of human histone demethylase UTY in complex with N05859b==
<StructureSection load='5fxv' size='340' side='right' caption='[[5fxv]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
<StructureSection load='5fxv' size='340' side='right'caption='[[5fxv]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fxv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FXV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FXV FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fxv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FXV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MN1:4-CARBOXYPIPERIDINE'>MN1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fxw|5fxw]], [[5fxx|5fxx]], [[5fxz|5fxz]], [[5fy0|5fy0]], [[5fy1|5fy1]], [[5fy4|5fy4]], [[5fy5|5fy5]], [[5fy7|5fy7]], [[5fy8|5fy8]], [[5fy9|5fy9]], [[5fyb|5fyb]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MN1:4-CARBOXYPIPERIDINE'>MN1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fxv OCA], [http://pdbe.org/5fxv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fxv RCSB], [http://www.ebi.ac.uk/pdbsum/5fxv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fxv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fxv OCA], [https://pdbe.org/5fxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fxv RCSB], [https://www.ebi.ac.uk/pdbsum/5fxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fxv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN]] Histone demethylase (By similarity).  
[https://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN] Histone demethylase (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H]]
[[Category: Large Structures]]
[[Category: Bountra, C]]
[[Category: Arrowsmith CH]]
[[Category: Delft, F von]]
[[Category: Bountra C]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Gileadi, C]]
[[Category: Gileadi C]]
[[Category: Johansson, C]]
[[Category: Johansson C]]
[[Category: Krojer, T]]
[[Category: Krojer T]]
[[Category: Kupinska, K]]
[[Category: Kupinska K]]
[[Category: Nowak, R]]
[[Category: Nowak R]]
[[Category: Oerum, S]]
[[Category: Oerum S]]
[[Category: Oppermann, U]]
[[Category: Oppermann U]]
[[Category: Pearce, N M]]
[[Category: Pearce NM]]
[[Category: Srikannathasan, V]]
[[Category: Srikannathasan V]]
[[Category: Fragment soaking]]
[[Category: Von Delft F]]
[[Category: Pandda]]
[[Category: Transferase]]
[[Category: X-ray fragment screening]]

Latest revision as of 16:31, 26 July 2023

Crystal structure of JmjC domain of human histone demethylase UTY in complex with N05859bCrystal structure of JmjC domain of human histone demethylase UTY in complex with N05859b

Structural highlights

5fxv is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.91Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UTY_HUMAN Histone demethylase (By similarity).

5fxv, resolution 1.91Å

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