5wn8: Difference between revisions

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 ==Structural Insights into Substrate and Inhibitor Binding Sites in Human Indoleamine 2,3-Dioxygenase 1==
-<StructureSection load='5wn8' size='340' side='right' caption='[[5wn8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+<StructureSection load='5wn8' size='340' side='right'caption='[[5wn8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5wn8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WN8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WN8 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5wn8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WN8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WN8 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BBJ:N-(3-bromo-4-fluorophenyl)-N-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide'>BBJ</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wmu|5wmu]], [[5wmv|5wmv]], [[5wmw|5wmw]], [[5wmx|5wmx]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BBJ:N-(3-bromo-4-fluorophenyl)-N-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide'>BBJ</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Indoleamine_2,3-dioxygenase Indoleamine 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.52 1.13.11.52] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wn8 OCA], [https://pdbe.org/5wn8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wn8 RCSB], [https://www.ebi.ac.uk/pdbsum/5wn8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wn8 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wn8 OCA], [http://pdbe.org/5wn8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wn8 RCSB], [http://www.ebi.ac.uk/pdbsum/5wn8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wn8 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/I23O1_HUMAN I23O1_HUMAN]] Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.<ref>PMID:17671174</ref>
+[https://www.uniprot.org/uniprot/I23O1_HUMAN I23O1_HUMAN] Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.<ref>PMID:17671174</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 20: / Line 19: @@
 </div>
 <div class="pdbe-citations 5wn8" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Indoleamine 2,3-dioxygenase]]
+[[Category: Homo sapiens]]
-[[Category: Batabyal, D]]
+[[Category: Large Structures]]
-[[Category: Bonanno, J B]]
+[[Category: Batabyal D]]
-[[Category: Karkashon, S]]
+[[Category: Bonanno JB]]
-[[Category: Lewis-Ballester, A]]
+[[Category: Karkashon S]]
-[[Category: Pham, K N]]
+[[Category: Lewis-Ballester A]]
-[[Category: Poulos, T L]]
+[[Category: Pham KN]]
-[[Category: Yeh, S R]]
+[[Category: Poulos TL]]
-[[Category: 3-dioxygenase 1 tryptophan heme inhibitor epacadostat incb024360]]
+[[Category: Yeh SR]]
-[[Category: Indoleamine 2]]
-[[Category: Oxidoreductase]]