5iu8: Difference between revisions

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 ==Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with compound 12f at 2.0A resolution==
-<StructureSection load='5iu8' size='340' side='right' caption='[[5iu8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+<StructureSection load='5iu8' size='340' side='right'caption='[[5iu8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5iu8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IU8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IU8 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5iu8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IU8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IU8 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6DZ:2-(FURAN-2-YL)-N~5~-[2-(4-METHYLPIPERAZIN-1-YL)ETHYL][1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZINE-5,7-DIAMINE'>6DZ</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=HTO:HEPTANE-1,2,3-TRIOL'>HTO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.002&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iu4|5iu4]], [[5iu7|5iu7]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6DZ:2-(FURAN-2-YL)-N~5~-[2-(4-METHYLPIPERAZIN-1-YL)ETHYL][1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZINE-5,7-DIAMINE'>6DZ</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=HTO:HEPTANE-1,2,3-TRIOL'>HTO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADORA2A, ADORA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iu8 OCA], [https://pdbe.org/5iu8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iu8 RCSB], [https://www.ebi.ac.uk/pdbsum/5iu8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iu8 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iu8 OCA], [http://pdbe.org/5iu8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iu8 RCSB], [http://www.ebi.ac.uk/pdbsum/5iu8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iu8 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
+[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 20: / Line 19: @@
 </div>
 <div class="pdbe-citations 5iu8" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Bacillus coli migula 1895]]
+[[Category: Escherichia coli]]
-[[Category: Bortolato, A]]
+[[Category: Homo sapiens]]
-[[Category: Cheng, R K.Y]]
+[[Category: Large Structures]]
-[[Category: Cooke, R M]]
+[[Category: Bortolato A]]
-[[Category: Deflorian, F]]
+[[Category: Cheng RKY]]
-[[Category: Dore, A S]]
+[[Category: Cooke RM]]
-[[Category: Errey, J C]]
+[[Category: Deflorian F]]
-[[Category: Guo, D]]
+[[Category: Dore AS]]
-[[Category: Heitman, L H]]
+[[Category: Errey JC]]
-[[Category: Ijzerman, A P]]
+[[Category: Guo D]]
-[[Category: Marshall, F H]]
+[[Category: Heitman LH]]
-[[Category: Segala, E]]
+[[Category: Ijzerman AP]]
-[[Category: Chimera]]
+[[Category: Marshall FH]]
-[[Category: G-protein-coupled receptor]]
+[[Category: Segala E]]
-[[Category: Integral membrane protein]]
-[[Category: Membrane protein]]
-[[Category: Thermostabilizing mutationsm]]