6ey7: Difference between revisions
Jump to navigation
Jump to search
m Protected "6ey7" [edit=sysop:move=sysop] |
No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Human cytomegalovirus terminase nuclease domain, Mn soaked, inhibitor bound== | |||
<StructureSection load='6ey7' size='340' side='right' caption='[[6ey7]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ey7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hcmva Hcmva]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EY7 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C3W:4-[(4-fluorophenyl)methyl-methyl-amino]-2,4-bis(oxidanylidene)butanoic+acid'>C3W</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |||
[[ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UL89 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10360 HCMVA])</td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ey7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ey7 OCA], [http://pdbe.org/6ey7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ey7 RCSB], [http://www.ebi.ac.uk/pdbsum/6ey7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ey7 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/TRM3_HCMVA TRM3_HCMVA]] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Hcmva]] | |||
[[Category: Albericio, F]] | [[Category: Albericio, F]] | ||
[[Category: Alvarez, M]] | [[Category: Alvarez, M]] | ||
[[Category: Machon, | [[Category: Bongarzone, S]] | ||
[[Category: Coll, M]] | |||
[[Category: Kaczmarska, Z]] | |||
[[Category: Machon, C]] | |||
[[Category: Nadal, M]] | [[Category: Nadal, M]] | ||
[[Category: | [[Category: Cytomegalovirus]] | ||
[[Category: Drug design]] | |||
[[Category: Inhibitor]] | |||
[[Category: Raltegravir]] | |||
[[Category: Terminase]] | |||
[[Category: Ul89]] | |||
[[Category: Viral protein]] | |||
Latest revision as of 11:38, 17 October 2018
Human cytomegalovirus terminase nuclease domain, Mn soaked, inhibitor boundHuman cytomegalovirus terminase nuclease domain, Mn soaked, inhibitor bound
Structural highlights
Function[TRM3_HCMVA] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation (By similarity). |
| ||||||||||||||||||