5dex: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, phenyl-ACEPC==
-<StructureSection load='5dex' size='340' side='right' caption='[[5dex]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+<StructureSection load='5dex' size='340' side='right'caption='[[5dex]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5dex]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DEX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DEX FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5dex]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DEX FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5E0:5-[(2R)-2-AMINO-2-CARBOXYETHYL]-1-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC+ACID'>5E0</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ddn|5ddn]], [[5ddx|5ddx]], [[5de4|5de4]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5E0:5-[(2R)-2-AMINO-2-CARBOXYETHYL]-1-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC+ACID'>5E0</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dex OCA], [http://pdbe.org/5dex PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dex RCSB], [http://www.ebi.ac.uk/pdbsum/5dex PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dex ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dex OCA], [https://pdbe.org/5dex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dex RCSB], [https://www.ebi.ac.uk/pdbsum/5dex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dex ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/NMDZ1_RAT NMDZ1_RAT]] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.<ref>PMID:15996549</ref>  [[http://www.uniprot.org/uniprot/NMDE1_RAT NMDE1_RAT]] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
+[https://www.uniprot.org/uniprot/NMDZ1_RAT NMDZ1_RAT] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.<ref>PMID:15996549</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 19: / Line 19: @@
 </div>
 <div class="pdbe-citations 5dex" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Glutamate receptor 3D structures|Glutamate receptor 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Conti, P]]
+[[Category: Large Structures]]
-[[Category: Hansen, K B]]
+[[Category: Rattus norvegicus]]
-[[Category: Mou, T C]]
+[[Category: Conti P]]
-[[Category: Pinto, A]]
+[[Category: Hansen KB]]
-[[Category: Sprang, S R]]
+[[Category: Mou T-C]]
-[[Category: Tamborini, L]]
+[[Category: Pinto A]]
-[[Category: Receptor]]
+[[Category: Sprang SR]]
-[[Category: Transport protein]]
+[[Category: Tamborini L]]