4igs: Difference between revisions
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==Crystal structure of human Aldose Reductase complexed with NADP+ and JF0064== | ==Crystal structure of human Aldose Reductase complexed with NADP+ and JF0064== | ||
<StructureSection load='4igs' size='340' side='right' caption='[[4igs]], [[Resolution|resolution]] 0.85Å' scene=''> | <StructureSection load='4igs' size='340' side='right'caption='[[4igs]], [[Resolution|resolution]] 0.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4igs]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4igs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IGS FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.85Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=64I:2,2,3,3,5,5,6,6-OCTAFLUOROBIPHENYL-4,4-DIOL'>64I</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4igs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4igs OCA], [https://pdbe.org/4igs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4igs RCSB], [https://www.ebi.ac.uk/pdbsum/4igs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4igs ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4igs" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4igs" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Cousido-Siah | [[Category: Cousido-Siah A]] | ||
[[Category: Farres | [[Category: Farres J]] | ||
[[Category: Klebe G]] | |||
[[Category: Klebe | [[Category: Martin MJ]] | ||
[[Category: Mitschler A]] | |||
[[Category: Martin | [[Category: Pares X]] | ||
[[Category: Mitschler | [[Category: Podjarny A]] | ||
[[Category: Pares | [[Category: Porte S]] | ||
[[Category: Podjarny | [[Category: Ruiz FX]] | ||
[[Category: Porte | [[Category: De Lera AR]] | ||
[[Category: Ruiz | [[Category: De la Fuente JA]] | ||
[[Category: | |||
[[Category: | |||