3c29: Difference between revisions

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==Cre-loxP Synaptic structure==
==Cre-loxP Synaptic structure==
<StructureSection load='3c29' size='340' side='right' caption='[[3c29]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3c29' size='340' side='right'caption='[[3c29]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3c29]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_p1 Bacteriophage p1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C29 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3c29]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_P1 Escherichia phage P1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C29 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C29 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hof|2hof]], [[3c28|3c28]], [[4crx|4crx]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cre ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10678 Bacteriophage P1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c29 OCA], [https://pdbe.org/3c29 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c29 RCSB], [https://www.ebi.ac.uk/pdbsum/3c29 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c29 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c29 OCA], [http://pdbe.org/3c29 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3c29 RCSB], [http://www.ebi.ac.uk/pdbsum/3c29 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3c29 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RECR_BPP1 RECR_BPP1]] Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state.  
[https://www.uniprot.org/uniprot/RECR_BPP1 RECR_BPP1] Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c2/3c29_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c2/3c29_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
Line 21: Line 20:
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c29 ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c29 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[Resolvase 3D structures|Resolvase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacteriophage p1]]
[[Category: Escherichia phage P1]]
[[Category: Duyne, G D.Van]]
[[Category: Large Structures]]
[[Category: Ghosh, K]]
[[Category: Ghosh K]]
[[Category: Di-aminopurine]]
[[Category: Van Duyne GD]]
[[Category: Dna integration]]
[[Category: Dna recombination]]
[[Category: Recombination-dna complex]]
[[Category: Synapsis]]

Latest revision as of 15:20, 30 August 2023

Cre-loxP Synaptic structureCre-loxP Synaptic structure

Structural highlights

3c29 is a 8 chain structure with sequence from Escherichia phage P1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RECR_BPP1 Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3c29, resolution 2.20Å

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