1tz9: Difference between revisions

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==Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41==
==Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41==
<StructureSection load='1tz9' size='340' side='right' caption='[[1tz9]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='1tz9' size='340' side='right'caption='[[1tz9]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1tz9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Entfa Entfa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TZ9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1tz9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_V583 Enterococcus faecalis V583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TZ9 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">uxuA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=226185 ENTFA])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tz9 OCA], [https://pdbe.org/1tz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tz9 RCSB], [https://www.ebi.ac.uk/pdbsum/1tz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tz9 ProSAT], [https://www.topsan.org/Proteins/NESGC/1tz9 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tz9 OCA], [http://pdbe.org/1tz9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tz9 RCSB], [http://www.ebi.ac.uk/pdbsum/1tz9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tz9 ProSAT], [http://www.topsan.org/Proteins/NESGC/1tz9 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UXUA_ENTFA UXUA_ENTFA]] Catalyzes the dehydration of D-mannonate (By similarity).  
[https://www.uniprot.org/uniprot/UXUA_ENTFA UXUA_ENTFA] Catalyzes the dehydration of D-mannonate (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tz/1tz9_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tz/1tz9_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Entfa]]
[[Category: Enterococcus faecalis V583]]
[[Category: Mannonate dehydratase]]
[[Category: Large Structures]]
[[Category: Acton, T A]]
[[Category: Acton TA]]
[[Category: Chen, Y]]
[[Category: Chen Y]]
[[Category: Cooper, B]]
[[Category: Cooper B]]
[[Category: Forouhar, F]]
[[Category: Forouhar F]]
[[Category: Hunt, J F]]
[[Category: Hunt JF]]
[[Category: Montelione, G T]]
[[Category: Montelione GT]]
[[Category: Structural genomic]]
[[Category: Shastry R]]
[[Category: Shastry, R]]
[[Category: Tong L]]
[[Category: Tong, L]]
[[Category: Xiao R]]
[[Category: Xiao, R]]
[[Category: Alpha-beta protein]]
[[Category: Lyase]]
[[Category: Nesg]]
[[Category: PSI, Protein structure initiative]]

Latest revision as of 10:30, 30 October 2024

Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41

Structural highlights

1tz9 is a 2 chain structure with sequence from Enterococcus faecalis V583. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

UXUA_ENTFA Catalyzes the dehydration of D-mannonate (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1tz9, resolution 2.90Å

Drag the structure with the mouse to rotate

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OCA