2al7: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==Structure Of Human ADP-Ribosylation Factor-Like 10C==
==Structure Of Human ADP-Ribosylation Factor-Like 10C==
<StructureSection load='2al7' size='340' side='right' caption='[[2al7]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='2al7' size='340' side='right'caption='[[2al7]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2al7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AL7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AL7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2al7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AL7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AL7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARL10C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2al7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2al7 OCA], [http://pdbe.org/2al7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2al7 RCSB], [http://www.ebi.ac.uk/pdbsum/2al7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2al7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2al7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2al7 OCA], [https://pdbe.org/2al7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2al7 RCSB], [https://www.ebi.ac.uk/pdbsum/2al7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2al7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ARL8B_HUMAN ARL8B_HUMAN]] May play a role in lysosome motility (PubMed:16537643). May play a role in chromosome segregation (PubMed:15331635).<ref>PMID:15331635</ref> <ref>PMID:16537643</ref>
[https://www.uniprot.org/uniprot/ARL8B_HUMAN ARL8B_HUMAN] May play a role in lysosome motility (PubMed:16537643). May play a role in chromosome segregation (PubMed:15331635).<ref>PMID:15331635</ref> <ref>PMID:16537643</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/al/2al7_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/al/2al7_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
Line 24: Line 24:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C]]
[[Category: Large Structures]]
[[Category: Atanassova, A]]
[[Category: Arrowsmith C]]
[[Category: Bochkarev, A]]
[[Category: Atanassova A]]
[[Category: Bochkarev A]]
[[Category: Dimov S]]
[[Category: Edwards A]]
[[Category: Ismail S]]
[[Category: Park H]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Dimov, S]]
[[Category: Sundstrom M]]
[[Category: Edwards, A]]
[[Category: Weigelt J]]
[[Category: Ismail, S]]
[[Category: Park, H]]
[[Category: Sundstrom, M]]
[[Category: Weigelt, J]]
[[Category: Gdp-binding]]
[[Category: Membrane trafficking]]
[[Category: Sgc]]
[[Category: Transport protein]]

Latest revision as of 10:25, 23 August 2023

Structure Of Human ADP-Ribosylation Factor-Like 10CStructure Of Human ADP-Ribosylation Factor-Like 10C

Structural highlights

2al7 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ARL8B_HUMAN May play a role in lysosome motility (PubMed:16537643). May play a role in chromosome segregation (PubMed:15331635).[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Okai T, Araki Y, Tada M, Tateno T, Kontani K, Katada T. Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation. J Cell Sci. 2004 Sep 15;117(Pt 20):4705-15. Epub 2004 Aug 25. PMID:15331635 doi:http://dx.doi.org/10.1242/jcs.01347
  2. ↑ Hofmann I, Munro S. An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility. J Cell Sci. 2006 Apr 15;119(Pt 8):1494-503. Epub 2006 Mar 14. PMID:16537643 doi:http://dx.doi.org/jcs.02958

2al7, resolution 1.85Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=2al7&oldid=3844110"