1kwt: Difference between revisions

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OCA

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 ==Rat mannose binding protein A (native, MPD)==
-<StructureSection load='1kwt' size='340' side='right' caption='[[1kwt]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
+<StructureSection load='1kwt' size='340' side='right'caption='[[1kwt]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1kwt]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KWT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KWT FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1kwt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KWT FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kwu|1kwu]], [[1kwv|1kwv]], [[1kww|1kww]], [[1kwx|1kwx]], [[1kwy|1kwy]], [[1kwz|1kwz]], [[1kx0|1kx0]], [[1kx1|1kx1]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MBL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kwt OCA], [https://pdbe.org/1kwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kwt RCSB], [https://www.ebi.ac.uk/pdbsum/1kwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kwt ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kwt OCA], [http://pdbe.org/1kwt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kwt RCSB], [http://www.ebi.ac.uk/pdbsum/1kwt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kwt ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/MBL1_RAT MBL1_RAT]] Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
+[https://www.uniprot.org/uniprot/MBL1_RAT MBL1_RAT] Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/1kwt_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/1kwt_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 30: / Line 29: @@
 </div>
 <div class="pdbe-citations 1kwt" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Mannose-binding protein|Mannose-binding protein]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Buffalo rat]]
+[[Category: Large Structures]]
-[[Category: Clark, D A]]
+[[Category: Rattus norvegicus]]
-[[Category: Drickamer, K]]
+[[Category: Clark DA]]
-[[Category: Feinberg, H]]
+[[Category: Drickamer K]]
-[[Category: Kolatkar, A R]]
+[[Category: Feinberg H]]
-[[Category: Ng, K K.S]]
+[[Category: Kolatkar AR]]
-[[Category: Park-Snyder, S]]
+[[Category: Ng KKS]]
-[[Category: Weis, W I]]
+[[Category: Park-Snyder S]]
-[[Category: C-type lectin]]
+[[Category: Weis WI]]
-[[Category: Calcium-binding protein]]
-[[Category: Immune system]]
-[[Category: Lectin]]
-[[Category: Sugar binding protein]]