5cis: Difference between revisions

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OCA

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 ==The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+==
-<StructureSection load='5cis' size='340' side='right' caption='[[5cis]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
+<StructureSection load='5cis' size='340' side='right'caption='[[5cis]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5cis]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CIS FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5cis]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CIS FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.58&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cis OCA], [http://pdbe.org/5cis PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cis RCSB], [http://www.ebi.ac.uk/pdbsum/5cis PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cis ProSAT]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cis OCA], [https://pdbe.org/5cis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cis RCSB], [https://www.ebi.ac.uk/pdbsum/5cis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cis ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/MASP2_RAT MASP2_RAT] Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 23: / Line 26: @@
 __TOC__
 </StructureSection>
-[[Category: Furze, C M]]
+[[Category: Large Structures]]
-[[Category: Gor, J]]
+[[Category: Rattus norvegicus]]
-[[Category: Nan, R]]
+[[Category: Furze CM]]
-[[Category: Perkins, S J]]
+[[Category: Gor J]]
-[[Category: Wallis, R]]
+[[Category: Nan R]]
-[[Category: Wright, D W]]
+[[Category: Perkins SJ]]
-[[Category: Complement activation]]
+[[Category: Wallis R]]
-[[Category: Cub1-egf-cub2]]
+[[Category: Wright DW]]
-[[Category: Hydrolase]]
-[[Category: Lectin pathway]]
-[[Category: Masp]]