1jnf: Difference between revisions

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==Rabbit serum transferrin at 2.6 A resolution.==
==Rabbit serum transferrin at 2.6 A resolution.==
<StructureSection load='1jnf' size='340' side='right' caption='[[1jnf]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='1jnf' size='340' side='right'caption='[[1jnf]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1jnf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/European_rabbit European rabbit]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JNF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JNF FirstGlance]. <br>
<table><tr><td colspan='2'>[[1jnf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JNF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jnf OCA], [http://pdbe.org/1jnf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jnf RCSB], [http://www.ebi.ac.uk/pdbsum/1jnf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jnf ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jnf OCA], [https://pdbe.org/1jnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jnf RCSB], [https://www.ebi.ac.uk/pdbsum/1jnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jnf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TRFE_RABIT TRFE_RABIT]] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.  
[https://www.uniprot.org/uniprot/TRFE_RABIT TRFE_RABIT] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jn/1jnf_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jn/1jnf_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</div>
</div>
<div class="pdbe-citations 1jnf" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1jnf" style="background-color:#fffaf0;"></div>
==See Also==
*[[Transferrin|Transferrin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: European rabbit]]
[[Category: Large Structures]]
[[Category: Bailey, S]]
[[Category: Oryctolagus cuniculus]]
[[Category: Hadden, J M]]
[[Category: Bailey S]]
[[Category: Hall, D R]]
[[Category: Hadden JM]]
[[Category: Leonard, G A]]
[[Category: Hall DR]]
[[Category: Lindley, P F]]
[[Category: Leonard GA]]
[[Category: Neu, M]]
[[Category: Lindley PF]]
[[Category: Winn, M]]
[[Category: Neu M]]
[[Category: Beta-alpha protein]]
[[Category: Winn M]]
[[Category: Bilobal]]
[[Category: Iron transport]]
[[Category: Metal binding protein]]

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