1xpi: Difference between revisions

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-[[Image:1xpi.gif|left|200px]]
- {{Structure
+==Crystal structure of the catalytic domain of E. coli pseudouridine synthase RluC==
-|PDB= 1xpi |SIZE=350|CAPTION= <scene name='initialview01'>1xpi</scene>, resolution 2.20&Aring;
+<StructureSection load='1xpi' size='340' side='right'caption='[[1xpi]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>
+<table><tr><td colspan='2'>[[1xpi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XPI FirstGlance]. <br>
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pseudouridylate_synthase Pseudouridylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.70 4.2.1.70] </span>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-|GENE= rluC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene></td></tr>
-|DOMAIN=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xpi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpi OCA], [https://pdbe.org/1xpi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xpi RCSB], [https://www.ebi.ac.uk/pdbsum/1xpi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpi ProSAT]</span></td></tr>
-|RELATEDENTRY=[[1v9k|1V9K]]
+</table>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpi OCA], [http://www.ebi.ac.uk/pdbsum/1xpi PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xpi RCSB]</span>
+== Function ==
-}}
+[https://www.uniprot.org/uniprot/RLUC_ECOLI RLUC_ECOLI] Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xp/1xpi_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xpi ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of the catalytic domain of E. coli pseudouridine synthase RluC'''
+==See Also==
+*[[Guide-independent Pseudouridine synthase|Guide-independent Pseudouridine synthase]]
+*[[Pseudouridine synthase 3D structures|Pseudouridine synthase 3D structures]]
-==About this Structure==
+__TOC__
-XPI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPI OCA].
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Pseudouridylate synthase]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Del Campo M]]
-[[Category: Campo, M Del.]]
+[[Category: Fenna R]]
-[[Category: Fenna, R.]]
+[[Category: Malhotra A]]
-[[Category: Malhotra, A.]]
+[[Category: Ofengand J]]
-[[Category: Ofengand, J.]]
-[[Category: catalytic domain]]
-[[Category: pseudouridine synthase]]
-[[Category: rluc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:52:48 2008''