5uii: Difference between revisions

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'''Unreleased structure'''


The entry 5uii is ON HOLD  until Paper Publication
==structure of DHFR with bound buformin and NADP==
<StructureSection load='5uii' size='340' side='right'caption='[[5uii]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5uii]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UII FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.351&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BFR:N-butyl-N-(diaminomethylidene)guanidine'>BFR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uii OCA], [https://pdbe.org/5uii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uii RCSB], [https://www.ebi.ac.uk/pdbsum/5uii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uii ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


Authors: Pedersen, L.C., London, R.E.
==See Also==
 
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
Description: structure of DHFR with bound buformin and NADP
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: London, R.E]]
[[Category: Escherichia coli]]
[[Category: Pedersen, L.C]]
[[Category: Large Structures]]
[[Category: London RE]]
[[Category: Pedersen LC]]

Latest revision as of 00:22, 29 June 2023

structure of DHFR with bound buformin and NADPstructure of DHFR with bound buformin and NADP

Structural highlights

5uii is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.351Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DYR_ECOLI Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

See Also

5uii, resolution 1.35Å

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