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==ALANINE 31 PROLINE MUTANT OF ROP PROTEIN, MONOCLINIC FORM==
==ALANINE 31 PROLINE MUTANT OF ROP PROTEIN, MONOCLINIC FORM==
<StructureSection load='1gmg' size='340' side='right' caption='[[1gmg]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1gmg' size='340' side='right'caption='[[1gmg]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1gmg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GMG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GMG FirstGlance]. <br>
<table><tr><td colspan='2'>[[1gmg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GMG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GMG FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1b6q|1b6q]], [[1f4m|1f4m]], [[1f4n|1f4n]], [[1gto|1gto]], [[1nkd|1nkd]], [[1rop|1rop]], [[1rpo|1rpo]], [[1rpr|1rpr]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gmg OCA], [http://pdbe.org/1gmg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gmg RCSB], [http://www.ebi.ac.uk/pdbsum/1gmg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gmg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gmg OCA], [https://pdbe.org/1gmg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gmg RCSB], [https://www.ebi.ac.uk/pdbsum/1gmg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gmg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX]] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.  
[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gm/1gmg_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gm/1gmg_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Glykos, N M]]
[[Category: Escherichia coli]]
[[Category: Kokkinidis, M]]
[[Category: Large Structures]]
[[Category: Transcription regulation]]
[[Category: Glykos NM]]
[[Category: Kokkinidis M]]

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