5tci: Difference between revisions

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 ==Crystal structure of tryptophan synthase from M. tuberculosis - BRD4592-bound form==
-<StructureSection load='5tci' size='340' side='right' caption='[[5tci]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
+<StructureSection load='5tci' size='340' side='right'caption='[[5tci]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5tci]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TCI FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5tci]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TCI FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=79V:(2R,3S,4R)-3-(2-fluoro[1,1-biphenyl]-4-yl)-4-(hydroxymethyl)azetidine-2-carbonitrile'>79V</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
-<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=79V:(2R,3S,4R)-3-(2-fluoro[1,1-biphenyl]-4-yl)-4-(hydroxymethyl)azetidine-2-carbonitrile'>79V</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tcf|5tcf]], [[5tcg|5tcg]], [[5tch|5tch]], [[5tcj|5tcj]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tci OCA], [https://pdbe.org/5tci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tci RCSB], [https://www.ebi.ac.uk/pdbsum/5tci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tci ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tci OCA], [http://pdbe.org/5tci PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tci RCSB], [http://www.ebi.ac.uk/pdbsum/5tci PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tci ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/TRPA_MYCTU TRPA_MYCTU]] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. [[http://www.uniprot.org/uniprot/TRPB_MYCTU TRPB_MYCTU]] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine (By similarity).
+[https://www.uniprot.org/uniprot/TRPA_MYCTU TRPA_MYCTU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 21: / Line 19: @@
 </div>
 <div class="pdbe-citations 5tci" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Tryptophan synthase]]
+[[Category: Large Structures]]
-[[Category: Structural genomic]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
-[[Category: Fisher, S L]]
+[[Category: Fisher SL]]
-[[Category: Hung, D T]]
+[[Category: Hung DT]]
-[[Category: Jedrzejczak, R]]
+[[Category: Jedrzejczak R]]
-[[Category: Joachimiak, A]]
+[[Category: Joachimiak A]]
-[[Category: Maltseva, N]]
+[[Category: Maltseva N]]
-[[Category: Michalska, K]]
+[[Category: Michalska K]]
-[[Category: Nag, P P]]
+[[Category: Nag PP]]
-[[Category: Schreiber, S L]]
+[[Category: Schreiber SL]]
-[[Category: Wellington, S]]
+[[Category: Wellington S]]
-[[Category: Allostery]]
-[[Category: Amino acid biosynthesis]]
-[[Category: Csgid]]
-[[Category: Heterotetramer]]
-[[Category: Lyase]]
-[[Category: Plp]]
-[[Category: Substrate channeling]]