5oa9: Difference between revisions
New page: ==Human translation re-initiation complex containing eIF2D== <StructureSection load='5oa9' size='340' side='right' caption='5oa9, resolution 1.80Å' scene=''> == S... |
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==Human translation re-initiation complex containing eIF2D== | ==Human translation re-initiation complex containing eIF2D== | ||
<StructureSection load='5oa9' size='340' side='right' caption='[[5oa9]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='5oa9' size='340' side='right'caption='[[5oa9]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5oa9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OA9 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5oa9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OA9 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5oa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oa9 OCA], [https://pdbe.org/5oa9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5oa9 RCSB], [https://www.ebi.ac.uk/pdbsum/5oa9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5oa9 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/EIF2D_HUMAN EIF2D_HUMAN] Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.<ref>PMID:20566627</ref> <ref>PMID:20713520</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5oa9" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5oa9" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Aylett CHS]] | ||
[[Category: | [[Category: Ban N]] | ||
[[Category: | [[Category: Boehringer D]] | ||
[[Category: | [[Category: Leibundgut M]] | ||
[[Category: | [[Category: Schaefer T]] | ||
[[Category: | [[Category: Weisser M]] | ||